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Sam Harris Revisits His Most Controversial Episode

Sam Harris speaks with Kathryn Paige Harden about behavioral genetics, moral luck, and the problem of blame. They discuss Harden's book Original Sin, the controversy over Charles Murray and Ezra Klein, why behavioral genetics remains taboo, the meaning of heritability, nature and nurture as feedback loops, why biological explanations can increase blame, psychopathy as a continuum, a hypothetical cure for evil, embryo selection and IVF, and other topics. Kathryn Paige Harden, Ph.D., is a Professor of Psychology at the University of Texas at Austin, where she directs the Developmental Behavior

The New Science of Cancer: A Conversation with Siddhartha Mukherjee (Ep. 485)

Sam Harris speaks with Siddhartha Mukherjee about the science of cancer. They discuss the updated edition of The Emperor of All Maladies, whether cancer is one disease or many, why prevention is so hard, inflammation and air pollution as carcinogens, the myth that cell phones cause cancer, liquid biopsies and Bayesian reasoning, immunotherapy and CAR T cells, drug pricing, the promise of AI in drug discovery, the state of American medical science, and other topics. Siddhartha Mukherjee is the author of The Song of the Cell; The Gene: An Intimate History, a #1 New York Times bestseller; and Th

Can AI Cure Loneliness?

Sam Harris speaks with Paul Bloom about our relationships with AI and the future of human connection. They discuss the surprising pace of AI progress, AI companions as a remedy for loneliness, the importance of mattering to other people, digitally resurrecting the dead, whether AI can be conscious, the moral failings of artists, what science actually knows about parenting, the ethics of apology, why late converts from Trump provoke outrage, and other topics. Paul Bloom is Professor of Psychology at the University of Toronto and Brooks and Suzanne Ragen Professor Emeritus of Psychology at Yale

The One Type of Candidate America Still Won’t Elect

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How College Miseducation Fuels the Far Left

SUBSCRIBE to gain access to all full-length episodes of the podcast at https://samharris.org/subscribe/ OR become a channel member to access episodes on YouTube. For those who can't afford the full subscription price, we offer partial scholarships https://www.samharris.org/subscribe/scholarship Stay updated on new episodes, essays, and events — subscribe to Sam Harris’s free newsletter: https://samharris.org/newsletter-signup/

The Truth About Thiel's “Secret Society”

Watch the full conversation in episode 482 of the Making Sense podcast. Making Sense explores philosophy, science, politics, and the ideas shaping how we see the world.

Why Is Everyone So Unhappy?

Sam Harris speaks with Alain de Botton about the psychology of unhappiness, the secular world's discomfort with ecstasy and ritual, psychedelics as a tool for self-discovery, Freud's legacy, AI as the ultimate mirror, the case against meritocracy, the cancel culture purity trap, the psychological meaning of death, and other topics. Alain de Botton is a writer, psychotherapist, and founder of The School of Life. He is interested in art, ideas, and the need for emotional education to help us manage relationships and make better choices. Website: alaindebotton.com, theschooloflife.com SUBSCRIB

To Pro-Israel Trump Voters: He Betrayed You Too

Watch the full conversation in episode 482 of the Making Sense podcast. Making Sense explores philosophy, science, politics, and the ideas shaping how we see the world.

The Tech Elite Who Want to Save Humanity, Not Humans

SUBSCRIBE to gain access to all full-length episodes of the podcast at https://samharris.org/subscribe/ OR become a channel member to access episodes on YouTube. For those who can't afford the full subscription price, we offer partial scholarships https://www.samharris.org/subscribe/scholarship Stay updated on new episodes, essays, and events — subscribe to Sam Harris’s free newsletter: https://samharris.org/newsletter-signup/

Tulsi Takes Orders from a Lei-Wearing, Surfer Dummy Guru

Watch the full conversation in episode 482 of the Making Sense podcast. Making Sense explores philosophy, science, politics, and the ideas shaping how we see the world.

He Would F* a Pig on National TV and Call It a Win for Farmers

Watch the full conversation in episode 482 of the Making Sense podcast.

Sam's Prediction from June 1st, 2026

From Sam's appearance on Ask Haviv Anything, June 1st, 2026

Sam Harris on Trump's Iran Deal: A Fully Humiliating Capitulation

SUBSCRIBE to gain access to all full-length episodes of the podcast at https://samharris.org/subscribe/ OR become a channel member to access episodes on YouTube. For those who can't afford the full subscription price, we offer partial scholarships https://www.samharris.org/subscribe/scholarship Stay updated on new episodes, essays, and events — subscribe to Sam Harris’s free newsletter: https://samharris.org/newsletter-signup/ Dave Columbo is featured at the start of the video: https://youtube.com/shorts/SU7n3NqmnOo?is=VSob8ttXwqnhLHxB

Is America Heading for a Debt Crisis? An Economist Explains

Sam Harris speaks with economist and Substack writer Noah Smith about the U.S. national debt, wealth inequality, and the economic consequences of AI. They discuss the mechanics of debt and inflation, the case for fiscal austerity, why the U.S. squandered low interest rates, modern monetary theory, how AI may restructure labor and ownership, the anti-billionaire politics of the American left, the degrowth movement and its failures, demographic decline and fertility trends, the role of smartphones in eroding democratic culture, and other topics. Noah Smith is an economics blogger and former fin

Wealthy Californians Have Already Fled

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More From Sam Live Recording (May 25, 2026)

The Phrase Mamdani Refuses to Condemn

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Chess Was Just the Beginning

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You Lose Interest the Moment You Realize It's AI

Sam Harris speaks with Susan Cain about writing, creativity, and what AI means for human culture. They discuss the future of books and reading, the tells AI inherits from good writers, why the advent of AI may spark a revival of the humanities, following your bliss, the ethics of curing sadness, the therapeutic potential of psychedelics, and other topics. Susan Cain is the author of the global sensation and #1 New York Times bestseller Quiet, and the instant #1 New York Times bestseller Bittersweet, an Oprah Book Club selection. Susan's new children's book Lucky & Norman will be published on

Christians Get Scrutinized. Islam Doesn't. Why?

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Why Is the NYT Platforming This Guy?

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How Tucker Gets Away With Everything

In this latest episode of the More From Sam series, Sam and Jaron talk about current events. They discuss the launch of Making Sense Community, Sam’s Ben Shapiro conversation, the New York Times’s embrace of Hasan Piker, Zohran Mamdani’s approach to Islamism, the misuse of the word “genocide,” AI-driven job displacement, and other topics. SUBSCRIBE to gain access to all full-length episodes of the podcast at https://samharris.org/subscribe/ OR become a channel member to access episodes on YouTube. For those who can't afford the full subscription price, we offer partial scholarships https://w

The Internet Needs a Civility Reset

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Why Gaza Isn’t a Genocide

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Michael Pollan on Consciousness, Psychedelics, and the Limits of Neuroscience

Sam Harris speaks with Michael Pollan about consciousness, the mind, and the self. They discuss Pollan’s new book, the relationship between consciousness and intelligence, whether consciousness is a product of evolution, the role of psychedelics in consciousness research, AI and the question of machine consciousness, the illusion of the self, and other topics. Michael Pollan is the John S. and James L. Knight Professor of Journalism at UC Berkeley and the author of eight books, including How to Change Your Mind, his 2018 account of the renaissance of scientific research into psychedelics. In

Hasan Piker Is the Left's Nick Fuentes

Become a Member to Watch More: https://www.youtube.com/@samharrisorg In this latest episode of the More From Sam series, Sam and Jaron talk about current events. They discuss the launch of Making Sense Community, Sam’s Ben Shapiro conversation, the New York Times’s embrace of Hasan Piker, Zohran Mamdani’s approach to Islamism, the misuse of the word “genocide,” AI-driven job displacement, and other topics. SUBSCRIBE to gain access to all full-length episodes of the podcast at https://samharris.org/subscribe/ OR become a channel member to access episodes on YouTube. For those who can't affor

"That's not language that I use" – Why Mamdani's Non-Answer Is Worse Than a Dog Whistle

In this latest episode of the More From Sam series, Sam and Jaron talk about current events. They discuss the launch of Making Sense Community, Sam’s Ben Shapiro conversation, the New York Times’s embrace of Hasan Piker, Zohran Mamdani’s approach to Islamism, the misuse of the word “genocide,” AI-driven job displacement, and other topics. SUBSCRIBE to gain access to all full-length episodes of the podcast at https://samharris.org/subscribe/ OR become a channel member to access episodes on YouTube. For those who can't afford the full subscription price, we offer partial scholarships https://w

Why the Stock Market Has Become a Casino

Sam Harris speaks with Lloyd Blankfein about finance, politics, and the state of American society. They discuss Blankfein’s memoir, Goldman Sachs and its role as a market maker, the 2007-2008 financial crisis, the AI investment bubble, wealth inequality and the rise of trillionaires, the crisis of antisemitism on the left and right, Trump-era corruption and the post-truth political environment, the national debt, and other topics. Lloyd Blankfein was chairman and CEO of Goldman Sachs from 2006 to 2018.

Does Ben Shapiro Regret His Vote For Donald Trump?

Sam Harris speaks with Ben Shapiro about their pre-election debate and the fractures on the right. They discuss Trump's second term surprises, familial corruption, tariff policy, the ideological world of Tucker Carlson, the spread of conspiracism on the right, antisemitism as the ur-conspiracy theory, JD Vance's political calculations, the future of Israel and the Palestinian question, and other topics. Ben Shapiro is Co-Founder of The Daily Wire and host of The Ben Shapiro Show, which has ranked among the top ten podcasts globally since 2018 and is the leading conservative podcast in the Uni

The Bar Is Now: Just Be Morally Sane

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Psychedelics Don't Distort Reality — They Reveal How Your Brain Constructs It

Get 30 Days of Waking Up Free → https://www.wakingup.com/makingsense Learn more → https://wakingup.com/LSD What you perceive as reality is a controlled hallucination your brain constructs moment by moment. And you are part of it. Unraveling the Dream explores what happens when that construction begins to fall apart—when the boundary between you and the world disintegrates, and the sense of self drops away. Revisiting Aldous Huxley’s early experiments with mescaline, examining the latest neuroscience of consciousness, and drawing on interviews with leading researchers, the film follows a cen

Two Pyromaniacs Lighting Matches

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Mamdani is Playing a Sinister Game

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Bret Weinstein Seems Reasonable. That's the Problem.

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Francis Fukuyama: The End of History Was Never What You Think

Sam Harris speaks with Francis Fukuyama about liberal democracy, American politics, and global order. They discuss the misunderstood thesis of "The End of History," how conservatism has mutated into ethno-nationalism, the self-defeating extremes of both identity politics and neoliberalism, the damage of Trump's second term, the war in Iran, the future of Israel, antisemitism on the left and right, and other topics. Francis Fukuyama is the Olivier Nomellini Senior Fellow at Stanford University's Freeman Spogli Institute for International Studies and Director of Stanford's Ford Dorsey Master's

This Is the Man Responding to Your Emergencies 😅

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The Democratic Party Has a Reckoning Coming

Sam Harris speaks with Rahm Emanuel about American politics, the state of the Democratic Party, and the 2028 presidential race. They discuss Emanuel’s possible presidential run, identity politics and the left’s cultural cul-de-sac, the Mississippi reading miracle, antisemitism on the left and right, the Gaza war, Netanyahu’s failures, U.S. policy toward China, wealth inequality, and other topics. Rahm I. Emanuel most recently served as the United States Ambassador to Japan. Previously, he was the 55th Mayor of the City of Chicago, a position he held until May 2019. Prior to becoming Mayor, fr

Just Cherish the Strait of Hormuz

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Why Dread What You Can't Change?

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Dems Are to Blame for Trump

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Escaping an Anti-Human Future: A Conversation with Tristan Harris (Ep. 469) FULL EPISODE

Sam Harris speaks with Tristan Harris about the dangers of AI and the race to build it. They discuss the new documentary The AI Doc: Or How I Became an Apocaloptimist, the lessons of The Social Dilemma, the arms race dynamics between AI labs, the "intelligence curse" and its implications for human political power, the psychology of tech CEOs indifferent to extinction risk, the possibilities of US-China coordination on AI safety, and other topics. Tristan Harris, described by The Atlantic as “the closest thing Silicon Valley has to a conscience,” is a technology ethicist and co-founder of the

A Library for People Who Don't Read

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